Cholesterol:
List
Cholesterol, as to the
question of good or bad, has been the brunt of inappropriate information. It is the
parent, as noted, of estrogen, testosterone and progesterone. These and biochemical
variations are intimately involved in propagation as relates to sexual differentiation.
Thus, with out cholesterol there would not exist life, leastwise as we know it. No
cholesterol, thereby, no hormones with out which there is no hereditary let alone
development of newer generations.
We are taught to recognize good and bad
cholesterol, which, unfortunately, through over simplification of the facts, imparts false
information. Let’s attempt to address the significance of cholesterol. It has been
stated that the body produces on the average 2/3rds of its cholesterol as an addition to
dietary sources required not only to produce the sex hormones, but cortisone, aldosterone,
vitamin D and others, which make up the steroid or sterol family of hormones. Steroid
means, literally, to reflect their familial relations to cholesterol. I have for years
been trying to find those geniuses who have determined the cholesterol values as well as
the ‘scientist(s)’ who have determined we lose a hundred and fifty thousand
brain cells each day.
We are given a figure that establishes values
under total cholesterol of being less than 200 as ideal. To make the situation bearable
‘statins’ which control HMG-Co A, an enzyme, needed to compound from natural
ingredients cholesterol and, thereby, sustaining the host of vital hormones as well as
vitamin D. Technically vitamin D ‘fits the bill,’ as accessed by chemical
evaluations, as a hormone, which metabolizes Calcium. Getting back to the magic number
200, which a decade or so ago was recognized as ‘good’ cholesterol at 250 and a
few decades earlier ‘good’ at 300mg. What exists is playing with ‘musical
chairs’ designed to promote levels, which allegedly represent normal. The
‘statins’ predilections are based on their success in lowering cholesterol with
out regard to natural measures, let alone cholesterol’s biochemical needs.
Inappropriate diets, together with the modern
disease of being ‘couch potatoes’ fortified by ‘ohing and ahing’
professional athletes, while gorging with ‘junk’ and convenience foods; refined
sugars, flour and oils contribute to cardio-vascular and other degenerative diseases. Our
damaged vessels maybe likened to plastering a wall, which has deteriorated, as a sort of
cosmetic measure to improve its appearance. Now, with the aforementioned habits, we lay
the groundwork for macrocytes, giant cells to engorge fats as well as lay down esters, by
diverting cholesterol from its natural function to repair arterial walls. What ensues is
our natural defenses attempt to compensate for our failure to take charge of our gift,
life and leaving to on ‘others’ to take charge. Even if the measures undertaken
could be successful, our sustained ‘bad’ habits tend to offset any gain, thus
‘bad’ or inappropriate activities as unsound diets and exercise promote
‘bad’ cholesterol, which relates to cholesterol’s diversion to correct our
failings. Not, only that, but alleged ‘cures’ promote deterioration. A wonderful
means of by-pass surgeries as well as grafts are but momentary stopgaps, while the
‘bad’ habits fail to be addressed with the ‘fixings’ ending up back at
‘square one.’ A plumber can repair your pipes damaged by caustics, but continual
‘bad’ habits of failed changes results in renewing damage. Think it over. Need
help get an honest as well as outstanding viewpoint. Poor habits, despite cosmetic
surgery, pharmaceuticals and neutraceuticals, are camouflaged measures, which fail to
reverse the ‘rotting’ that persists within our cells!
Suggested sources: Biochemistry 2nd
Edition, Wiley, 1995, Authors Drs. Donald and Judith Voet; Pages: Cholesterol:
Biosynthesis 560,690-703; plasma levels 324; 698-699 lanosterol; esterfication of 321;
utilization of 703-704; Textbook of Biochemistry with Clinical correlations 3rd
Edition, Wiley-Liss, May 1993: Pages 204,902,1156; atherosclerosis 446;
hpercholesterolemia 445; polyunsaturated fatty acids and heart disease; structure and
function 438-439;synthesis 439-446; vitamin D synthesis 448-449;steroid hormone synthesis
905-907, 908f.
Salt or Sodium: List
More people die from too
little than from too much! This maybe witnessed as a provocative assertion, but
electrolytes are essential to survival. It has been the custom for years to supply salt,
that is as sodium to those who perspire profusely while functioning in warm or
significantly hot climates or if not in an excessively warm environment being exposed to
summer weather. I recall being given 1-2 salt tablets, while functioning as a laborer
during the summer months, as an endeavor to compensate for salt, primarily sodium, loss.
Heat exhaustion can readily respond to appropriate electrolyte solutions containing salts,
while the worse condition from electrolytic imbalance, heat stoke, can be irreversible and
result in death.
The effects on a frog’s leg impressed me
during an experiment, which involved electrical stimulating of its muscle. On one end the
muscle was anchored, while on the other a stylus formed a graph, which evidenced muscle
contraction as electricity coursed through the muscle. The muscle was gradually stressed
by adding weights of increasing values. During the procedure, these actions fatigued the
muscle until it could no longer contract. Amazingly dripping an electrolyte solution of
salts (Sodium, Potassium) revived the muscle function. The solution being used was and
still is referred to as Ringers Lactate. I made it a habit to oppose the classic Ben
Casey’s 5% glucose and water by administering Ringer’s Lactate to my patients.
Glucose was administered either to elevate a lower or impending or actual case of low
blood pressure by adding saline (salt) to the solution, referred to as 5% glucose in
saline. On the other hand if the blood pressure was high 5% glucose was combined with
water as a means to reduce of BP. This was the first instance; I encountered as medical
‘Musical chairs’ or guesswork. This is a practice, which continues to this day
as an oversimplification of real physiological effects A search of the literature will
reveal that excess glucose up ends electrolyte balance, which exists between the salts
sodium and potassium. An example, as noted in diabetes and to an extent, can be duplicated
in relation to cell membranes by introducing free glucose, which forces sodium into the
cell and exits sufficient potassium past the cell membrane, thus elevating potassium
levels in the circulation. This activity reflects a body chemistry function referred to as
the ‘sodium pump.’ Nutrient intakes and cellular excretion of wastes are
dependent upon harmonious function of these electrolytes in sustaining vitality. It is
obvious there are no quick solutions to upending not only the electrolyte balances, but of
the chemistries, which support life.
Now a question, if such is the case, how
significant is the suggestions to reduce salt to counter elevated blood pressure, as well
as compensate for heart failure, etc. We are biochemical individualized and as such must
not be stereotyped. We must avoid excesses, meaning methods, which direct us to restrict
or add factors with out heeding underlying results. I can recall a case of a female
patient, who suffered from excessive fluid retention, which made her legs to appear
markedly edematous. She popped 10 as much as 20 Lasex tablets a day to control her water
retention to no avail. I suggested she take a few teaspoons full of salt in a glass of
iced water. She found the idea repugnant. Nevertheless at a follow up visit, she advised
me of her miraculous loss of water by ingesting 4 to 6 salt (sodium) tablets. She claimed
not only did the edema leave her legs, but, she experienced a 15-20 pound loss of weight.
What had been corrected was an imbalance as relates to electrolytes, a reflection of the
inappropriate use of a powerful diuretic.
Did you ever wonder as to the severe cramping
of well-trained athlete’s muscles and its ultimate cause? There they are guzzling a
beverage loaded with excess sugars, mainly glucose (dextrose) with the involved limb
encased with ice packs. They are suffering from salt deprivation, not unlike the
frog’s leg as cited in the aforementioned experiment. Oh, yes, severe diarrhea as
experienced in those exposed to pathogens as E.coli, clostridium difficile make dramatic
responses to beverages maximizing salts. If you have questions reach out to me. Never
undertake any measures, which fail to consider appropriate intakes or related factors,
which are capable of correcting an imbalance. Obviously, any problems would be moot in the
presence of sound nutrition and exercise functions! My patient was way off balance by
taking pharmaceuticals with out recognizing limitations.
Suggested resources: Biochemistry, 2nd
Edition, 1995, Wiley Authors; Donald and Judith Voet NA-glucose support 531-532f; NA
channels 1293-1295; (NA-K pump) ATPase 525-527, mechanism of, 525-526F; Textbook of
Biochemistry with clinical correlations, 3rd Edition. Wiley 1992, Editor Thomas
M. Devlin, NA in acid-base balance 1054-1056; NA channels 220,221; NA, K ATPASE pump 226,
226-230.
Drugs (ethical):
List
As long as Homo sapiens
exist, there will forever be a search for Ponce de Leon’s Fountain of Youth or a
‘pill,’ which will satisfy our curiosity, through human ‘ingenuity’
purporting solutions that potentiate survival and ultimately perpetuating youthful
longevity. Most of what we attempt to develop underscores our desire to facilitate success
by proving nature or God, regardless of persuasion, can be matched by human ingenuity.
Over the eons, we have been at a perpetual search to sustain youthful health as well as
rule any element, which we as scientists, physicians, ‘witch doctors, oracles,
‘Merlins’ and a host of related health care persons, deem with in the grasp of
attainment.
When I first encountered the Physicians Desk
Reference (PDR) it was a thin book of but a couple hundred pages. Now, the PDR, as for
example the 53rd-54th Editions are over 2" thick and well
beyond 1500 pages. The PDRs as well as smaller manuals, the latter addressing more common
used pharmaceuticals, are the sources for indications, chemical structures, usage and
adverse effects. They serve as bibles, which dictate supply and demand as relates to
physicians (DO, MD) care. Much of what is presented or prescribed is based upon
advertisements, with the lifting of ethical questions as to the propriety of clinician
control. The public is deluged by propaganda, which bypasses professional control,
reinforces current thinking, thus creating a partnership between patients and clinicians.
I have been a proponent of ‘taking charge’ of ones gift, LIFE. However, I lean
towards the direction of sound nutritional and physical measures, which are designed to
sustain immune function, thus promoting effective activities of daily living.
Drugs, as pharmaceuticals, are toxic compounds,
which are created to promote ‘cures’ by influencing through governing their
effects on living chemistries. Think of them as poisons, which are modified by scientists
and or pharmacologists to control lethal influences. Ethical drugs, for example digitalis,
antibiotics, diuretics, anti-epileptics and a host of others, are successfully promoted to
effect ‘cures.’ Digitalis toxic effects influences cardiac function, which
‘irritates’ cardiac muscles into increased activity. This may be somewhat
similar to whipping a tired horse. Eventually, the pharmaceutical activity vanishes and
with that a combination of other medicines are maneuvered, literally, to effect governable
toxins, which will get a few more ‘miles’ out of a tired heart. Incidentally, at
no time is there any attempts concerning the significance of curbing unsound practices as
relates to health, being encouraged.
Now you have been handed a befuddling thought
as to pharmaceuticals being governable toxins. The levels of toxicity are based on lethal
levels, as for example LD 50, which represent the limit of toxic effects as a measure to
make the drug safe. Thus, every time you ingest an ‘ethical’ drug, you are at
risk of adverse reactions. Take a gander at the PDR and armed with the information
approach your practitioner as to whether the ‘cure’ is worse than the disease!
Cancer therapy has not as yet gotten out of the barbaric age. The ‘new age’ has
yet to direct individuals to assume liability or success, which relate to them taking
charge.
References: The Physicians Drug Reference, 53rd
Edition, 1999; Monthly Prescribing.
Reference New This Month: October 2000; Triple
i, Prescribing Guide, Issue 3, 2000.
Food Technology:
List
Refined nutrients, not even
a self-respecting rodent would eat. Foods are altered to meet several perceptions. First
off with the advent of no longer dependent upon homegrown products, that is directly from
the farm to you or as milk advertised in the past "from moo to you," we are
faced with shelf life. That is how to protect foods from deterioration. We can vacuum
pack, irradiate, chemically treat or alter foods to sustain shelf life. One of the
measures is to refine foods, which by removing essential nutrients makes them less prone
to insect infestation, fungi or rodent infestation. I have, already, mentioned, "No
self respecting rodent would be caught indulging in altered foods."
Altering foods, as for example refining whole
grain into white flour produces an impoverished commodity, which has most of its vitamins
removed, if not all. What remains is a ‘refined’ ‘junk’ valued
product, which finds its vitamin content being fed to live stock. Think of that, the
livestock, as well as pets are likely to be healthier by virtue of food techniques, which
to prevent losses, are redirected to them. Oh, we add a few of the B vitamins to
‘enrich’ ‘refined’ foods. B1, B2, Folic acid are but a few of
essential nutrients that are added by mandate from The Food and Drug Administration (FDA)
as responses to technical altered commodities.
Aesthetic alterations or
‘enrichments’ are created to satisfy our perceptions. Oranges, pop sodas as pink
lemonade, colas have their colors treated with additives, which have, frequently, been
cited as carcinogenic compounds. When have you last seen a ‘real’ colored
orange, which when picked has variants of green and orange hues, but at the market is
covered with an even orange color, a technological created color, which has been accepted,
despite being a potential carcinogen. Monosodium glutamate is added to foods to
artificially enhance taste buds, despite side effects of bloating, musculo-skeletal
weakness or the so-called ‘Chinese Restaurant Syndrome.’ I, nearly, exanguinated
from an additive until I, after eight years, determined that the presence of sulfate,
which was used to give lettuce, melons, etc fresh green looks, was the culprit. I have
ceased to use soaping compounds as found in public lavatories, because they contain sodium
lauryl sulfate. My hands swelled turned a ghastly blue as if the prelude to gangrene. A
few weeks ago, as I perused the contents of a calcium magnesium supplement, what do you
think I discovered? I found it contained sodium lauryl sulfate. Can you picture what would
happen, had I not detected the sulfate or let’s put it to being aware of what I take
in, as most of us tend to fail to do, I’d could have ended up a medical statistic.
Not, only a medical statistic, but a physicians dream being plied with H2 blockers, many
of which are purchased as over the counter (OTC) drugs to correct a sulfate induced
gastric ulcer. What represents grateful relief, can camouflage an on going serious problem
with the development of a penetrating ulcer. How many suffers of asthma are treated by
manipulating pharmaceuticals, while they, actually, are suffering from sulfate ingestion.
There are numerous instances of impaired health, which a drug or combination alleviates at
the expense of getting at ‘the bottom’ of the actual cause. We suffer not from
deficiencies in drugs but of nutrients, some of which are created by drugs. I hope I have
peaked your interest as to our vulnerability to modern technology.
References Food and Drug administration
publications, PDR, Internet. And yours truly!
Biochemical
Individuality:
List
Differences do count! A few
decades ago, I became convinced that we are not clones, but biochemical individualized. It
has been, obvious, that’s definitely, at least to me that we respond as individuals
to varying situations. The time of day as relates to biological (diurnal) rhythms,
socio-economic effects, personality, moment of circumstances, sexual as well as individual
response determine outcomes. As decades past, I had a ethereal episode, where by a chap in
a gray flannel suit, what was reflected back than as a Madison Avenue personality,
materialized in my office, sat down for what seemed a mere moment and handed me Roger J.
Williams, Ph.D. book, Biochemical Individuality, The
Basis for the Genetotrophic Concept.
Here it was a must reading if you and the scientific world are determined to acknowledge
physiologic differences as determinants of sustaining immune function, thus sustaining
activities of daily living. I quote Williams, which is a virtual reflection of my
experiences. He pointed out," If we consider the possibility that among the numerous
measurable attributes that human beings possess there may be many which are not
mathematically correlated, we are confronted with an idea which is opposed to the basic
dichotomy of normal and abnormal mentioned above. If 0.95 of the population is normal with
respect to one measurable item, only 0.902 (0.95 sq.) would be normal with respect to two
measurable items and 0.60 (0.95 10 sq.) and 0.0059 (0.95 100sq.), respectively, would be
normal with regard to 10 and 100 uncorrelated items." He, further inferred, "The
existence in every human being of a vast array of attributes which are potentially
measurable (whether by present methods or not); and probably often uncorrelated
mathematically, makes quite tenable the hypothesis that practically every human being
is a deviate in some respects. Some deviations are, of course, more marked and some
more important than others. If this hypothesis is valid, a newborn cannot be validly be
considered as belonging in either one of two groups, normal and abnormal. Substantially
all of them are in a sense "abnormal." In the majority, the
"abnormalities" may be well enough concealed so that they are not revealed by
clinical examination, though they may easily have an important bearing upon the
susceptibility of the individual child to disease later in life. Among the distinctive
differences observed in the mineral analysis study were: (1) nearly a six fold differences
between two individuals (no overlapping in values) in urinary calcium excretion, (2)
nearly a 3-fold variation in plasma magnesium, (3) over a 30 percent difference (no
overlapping value) in the sodium content of blood cells, (4) a 4-fold variation (with no
overlapping of values in 21 to 25 samples, respectively) in salivary sodium, (5) a 5-fold
variation in salivary magnesium with no overlapping values in 7 to 15 samples,(60 taste
threshold values that often differed consistently from individual to individual over a
20-fold range." Finally, he wrote in a summary, " On the occasion of celebrating
its 200th anniversary, Columbia University organized a large conference on the
"Unity of knowledge" One section of the conference had its problem "
Man’s Understanding of His Own Nature," and one questioned asked was, "Is
there any likelihood that a single recognizable picture of man can be discerned among the
many detailed and varied arts and sciences?" This represents a current mode of
thought which is incompatible with the idea of biological individuality." Mind you
John Wiley & Sons published the aforementioned book, originally. And copyrighted by
Dr. Roger Williams in 1956.
References: Biochemical Individuality, as
noted: My as yet unpublished, tentatively titled The Doctors Book of Nutrition and
Exercise Programmed to Sustain the Gift, LIFE. If there exists a demand it is possible
that my newest would be available, either by funding chapters, down loading or revealed as
supporting documents in www.lifesustainer.com.
Musculo-skeletal and
systems:
List
Exercise makes a profound
difference. How well prepared are you? We are a nation, ‘hell bent for leather’
growing fatter by each minute. In the ‘good’ ole days, with the scarcity of
food, that is back during the ‘Great Depression’ of the end of the 20s and the
advent of the 30s, obesity when perceived, especially, of an infant attested to albeit, a
false status of being ‘wealthy.’ In this modern era there is no reason for
obesity becoming a common norm. We have the divesting in many of the public schools of
athletic or gymnastic skills. Now, when you combine that with restricted physical
activities, which find children, their elders plunked down in front of TVs and glued to
PCs, while playing games and ‘surfing’ the Internet, together with chats, you
have factors, which fail to burn off calories. What makes it worse is a generation of
‘oohers and ahers’ reveling in the exploits of athletes. Imagine getting paid
millions to perform while the audience physically deteriorates. Compounding a sedentary
society, which packs in thousands if not a few tons of useless high calories
‘junk,’ convenience foods together with other empty calories as indulging with
refined sugars, flours and high temperature caustic lye treated oils. What exist are
overwhelming intakes of mainly useless calories, which together with an immobile society,
fails to burn off the accumulated calories. Thus, we become fatter by the minute and with
it all promoting degenerative disease states. Cardio-vascular, gastro-enterologic,
neurological, endocrine, immune systems become impaired. We turn to nips and tucks to
sculpture youthful appearances, but with in our bodies rot continues unabated.
We definitely do not store exercise. Early in
life as a child or teenager, we rebound rabidly from being restricted by disease or
accident, but as we age retarded activity is faced by, a seemingly, lengthening recovery
intervals and there may come a point where we just throw the sponge in. I am somewhat, so
it may appear, insensitive to individuals who take to appliances such as wheel chairs,
while their health has not evidenced ‘real’ musculo-skeletal decline. I am not
referring to the many who have no alternatives to get about, though I would not be
surprised by the exceptions who try with all their might to achieve mobility despite the
odds and succeed. Observing an, obvious, not fully handicapped person, who perhaps has
slowed down or for convenience is relocated to a wheel chair or worse an automated
electric charged functioning apparatus, which promote musculo-skeletal deterioration and
accompanying cardiovascular and respiratory dysfunction, is, sadly, demeaning. First comes
the mobile chair, which is followed by a stationary chair, than being bedridden and
shortly, after followed by death. I have observed individuals, happily, cruising up and
down streets in mobile chairs, totally, unaware of degenerative changes developing with in
their cardiovascular, respiratory, gastrointestinal, endocrine, neurological and immune
systems as relate to a cascade of events, which from imposed states of ‘oohing’
and ‘ahing’ athletes sustain modern inertia, being a non performer!
I have observed individuals cruising up and
down the side walks in mobile chairs, oblivious to the degeneration going on in the
aforementioned systems, other than ‘coping’ out by suggesting, "Well, I am
getting old, what more can I expect? After all, I am wheel chaired bound!" What is
going on is voluntarily or if institutionalized the involuntary use of pharmaceutical
‘straight jackets’ which do not promote rehabilitation, but speed up death! What
develops is becoming chair bound followed by being bedridden. You know the rest of the
story! I, have the misfortune of seeing a renowned musician navigating a mobile chair.
Yes, it has improved his means to get about, but with it all, despite smiles, there exists
by this stage a total loss of former lower extremity musculo-skeletal mobility and with
that the declining support of the aforementioned vital systems. I am grateful that I can
get about, thus my opinions, as unrelated to experience of a handicapped person, maybe
misconstrued as being calloused. Not really, I believe in using every means to promote
musculo-skeletal function. In fact, the effort as predicted by the degree of handicap and
effort to overcome, can have a positive effect If one must use a mobile wheel chair, I
hope they continue to sustain physical functions, by pushing their handicap(s) to its
limits.
References: My yet to be published The Doctors
Book of Nutrition and Exercise Programmed to Sustain the Gift, Life! |
